Structure of PDB 5un8 Chain C

Receptor sequence
>5un8C (length=429) Species: 9606 (Homo sapiens) [Search protein sequence]
HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNMLYSPQMALKLALTEWLQEFSVT
LEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAKFE
EMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRS
HSSAQFLIGDQEPWAFRGGLAGEFQRLLP
3D structure
PDB5un8 Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
ChainC
Resolution2.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C M622 W645 W679 M357 W380 W414
BS02 peptide C Y69 N175 F223 Y11 N117 F165
External links
PDB RCSB:5un8, PDBe:5un8, PDBj:5un8
PDBsum5un8
PubMed28319083
UniProtO60502|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)

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