Structure of PDB 5uht Chain C

Receptor sequence
>5uhtC (length=237) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
LKRIDRMKTEFIANISHELRTPLTAIKAYAETIYNSLGELDLSTLKEFLE
VIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEF
ASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKY
VKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSSLTYEVPGTG
LGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR
3D structure
PDB5uht A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
ChainC
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP C N380 K383 Y384 I416 I424 R430 G441 G443 L446 F472 N137 K140 Y141 I173 I181 R187 G198 G200 L203 F229
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

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Molecular Function

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Biological Process
External links
PDB RCSB:5uht, PDBe:5uht, PDBj:5uht
PDBsum5uht
PubMed29235472
UniProtQ9WZV7

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