Structure of PDB 5u1q Chain C

Receptor sequence
>5u1qC (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
AAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLC
HLQKVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLL
RHCCT
3D structure
PDB5u1q Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C R438 K478 H479 Y480 L481 M495 R16 K56 H57 Y58 L59 M72
BS02 peptide C D496 Q499 D73 Q76
External links
PDB RCSB:5u1q, PDBe:5u1q, PDBj:5u1q
PDBsum5u1q
PubMed29083893
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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