Structure of PDB 5tyi Chain C

Receptor sequence
>5tyiC (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQ
KVKHYLILPSEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHC
CTRV
3D structure
PDB5tyi Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target.
ChainC
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C R438 S460 V468 K478 H479 Y480 L481 M495 I518 R13 S35 V43 K53 H54 Y55 L56 M69 I92
External links
PDB RCSB:5tyi, PDBe:5tyi, PDBj:5tyi
PDBsum5tyi
PubMed29083893
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

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