Structure of PDB 5thp Chain C

Receptor sequence
>5thpC (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
LIDVVVVCDESNSIWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVV
FNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRS
ATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTK
NLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFS
3D structure
PDB5thp Dramatic and concerted conformational changes enable rhodocetin to block alpha 2 beta 1 integrin selectively.
ChainC
Resolution3.006 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D180 S182 S184 T250 D283 D9 S11 S13 T77 D110
External links
PDB RCSB:5thp, PDBe:5thp, PDBj:5thp
PDBsum5thp
PubMed28704364
UniProtP17301|ITA2_HUMAN Integrin alpha-2 (Gene Name=ITGA2)

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