Structure of PDB 5t6p Chain C

Receptor sequence

>5t6pC (length=216) Species: 10090 (Mus musculus) [Search protein sequence]

DVLMTQTPLSLPVSLGDQASISCRSSQTIVHSNGKIYLEWYLQKPGQSPK
LLIYRVSKRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHVP
WTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDIN
VKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE
ATHKTSTSPIVKSFNR

3D structure

PDB

5t6p Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.

Chain

Resolution

1.97 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	H31 Y37 E39 R55 F94 G96 V99 W101	H31 Y37 E39 R55 F94 G96 V99 W101

External links

PDB	RCSB:5t6p, PDBe:5t6p, PDBj:5t6p
PDBsum	5t6p
PubMed	28025250

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