Structure of PDB 5pb4 Chain C

Receptor sequence
>5pb4C (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLT
GIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
3D structure
PDB5pb4 Crystal Structure of a Factor VIIa complex
ChainC
Resolution2.43 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9RS C H253 C254 D256 K257 G297 S399 C400 K401 S404 S423 W424 H41 C42 D44 K45 G85 S180 C181 K182 S185 S204 W205
BS02 CA C E270 D272 E275 E280 E58 D60 E63 E68
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5pb4, PDBe:5pb4, PDBj:5pb4
PDBsum5pb4
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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