Structure of PDB 5pb3 Chain C

Receptor sequence
>5pb3C (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTW
YLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
3D structure
PDB5pb3 Crystal Structure of a Factor VIIa complex
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9S1 C L237 H253 C254 D256 K257 G297 S399 C400 K401 S404 W424 G425 G427 C428 L25 H41 C42 D44 K45 G85 S183 C184 K185 S188 W208 G209 G211 C212
BS02 CA C E270 D272 E275 E280 E58 D60 E63 E68
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5pb3, PDBe:5pb3, PDBj:5pb3
PDBsum5pb3
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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