Structure of PDB 5pb2 Chain C

Receptor sequence
>5pb2C (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTW
YLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
3D structure
PDB5pb2 Crystal Structure of a Factor VIIa complex
ChainC
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA C E270 D272 E275 E280 E58 D60 E63 E68
BS02 9RP C H253 S399 C400 K401 S404 S423 W424 H41 S183 C184 K185 S188 S207 W208
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:5pb2, PDBe:5pb2, PDBj:5pb2
PDBsum5pb2
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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