Structure of PDB 5pau Chain C

Receptor sequence
>5pauC (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTW
YLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
3D structure
PDB5pau Crystal Structure of a Factor VIIa complex
ChainC
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C E270 D272 E275 E280 E58 D60 E63 E68
BS02 7ZJ C H253 D256 G297 D398 S399 C400 S423 W424 G425 G427 H41 D44 G85 D182 S183 C184 S207 W208 G209 G211
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5pau, PDBe:5pau, PDBj:5pau
PDBsum5pau
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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