Structure of PDB 5oes Chain C

Receptor sequence

>5oesC (length=447) Species: 4113 (Solanum tuberosum)

IVDPHDIDPKLVQKLANDALVWCSLRGLLVGDRNSERSGTVPGVDMVHAP
VALIPMSFPESHWKQACEVAPIFNELVDRVSQDGEFLQQSLSRTRKVDPF
TSRLLEIHSKMLEINKIEEIRLGLHRSDYMLDEQTKLLLQIELNTISSSF
PGLSCLVSELHRSLLQQYREDIASDPNRIPANNAVNQFAEALAKAWNEYG
DPRAVIMFAVQAEERNMYDQHWLSASLRERHQVTTIRKTLAEIDALGELQ
QDGTLVVDGQAVAVIYFRAGYAPSDYNSESEWKARLLMEQSRAVKCPSIS
YHLAGSKKIQQELAKPNVLERFLENKDDIAKLRKCFAGLWSLDESDIVKD
AIDRPELYVMKPQNNIYGEDVRDALLKLYILMQRIFPKISHSILMREGIS
HKEQTISELGIYGTYLRNKTEVVINQQAGYLMRTKVSFAVLDSIYLV

3D structure

• PDB: 5oes Effector gene birth in plant parasitic nematodes: Neofunctionalization of a housekeeping glutathione synthetase gene.
• Chain: C
• Resolution: 2.48 Å

Enzymatic activity

• Enzyme Commision number: 6.3.2.3: glutathione synthase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	C	M141 I152 E153 K318 V370 K372 N381 Y383 M408 Q409 R410 I411 E434 K461	M130 I141 E142 K307 V359 K361 N365 Y367 M382 Q383 R384 I385 E408 K435
BS02	3GC	C	R137 I157 S158 S160 E225 N227 Q231 R279 Y282	R126 I146 S147 S149 E214 N216 Q220 R268 Y271
BS03	MG	C	D139 E153 E434	D128 E142 E408

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0004363 glutathione synthase activity
• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0043295 glutathione binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006750 glutathione biosynthetic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:5oes, PDBe:5oes, PDBj:5oes
• PDBsum: 5oes
• PubMed: 29641602
• UniProt: M1CSC4