Structure of PDB 5o0b Chain C

Receptor sequence
>5o0bC (length=154) Species: 561007 (Mycobacteroides abscessus ATCC 19977) [Search protein sequence]
MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINAGMFTVDERIEM
IRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQ
MNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLL
GKLR
3D structure
PDB5o0b Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew.
ChainC
Resolution1.735 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) H17 R90 S127
Catalytic site (residue number reindexed from 1) H17 R87 S124
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9FE C G8 S9 F10 H17 K87 G88 G8 S9 F10 H17 K84 G85 MOAD: Kd=66uM
BS02 9FE C G16 H17 G88 R90 S126 S127 G16 H17 G85 R87 S123 S124 MOAD: Kd=66uM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5o0b, PDBe:5o0b, PDBj:5o0b
PDBsum5o0b
PubMed28648615
UniProtB1MDL6|COAD_MYCA9 Phosphopantetheine adenylyltransferase (Gene Name=coaD)

[Back to BioLiP]