Structure of PDB 5o0a Chain C

Receptor sequence
>5o0aC (length=153) Species: 561007 (Mycobacteroides abscessus ATCC 19977) [Search protein sequence]
MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLIAGMFTVDERIEMI
RESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQM
NKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLG
KLR
3D structure
PDB5o0a Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew.
ChainC
Resolution1.805 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H17 R90 S127
Catalytic site (residue number reindexed from 1) H17 R86 S123
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9FH C T14 G16 H17 R90 T118 V125 S126 S127 T14 G16 H17 R86 T114 V121 S122 S123 MOAD: Kd=0.58mM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5o0a, PDBe:5o0a, PDBj:5o0a
PDBsum5o0a
PubMed28648615
UniProtB1MDL6|COAD_MYCA9 Phosphopantetheine adenylyltransferase (Gene Name=coaD)

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