Structure of PDB 5nj8 Chain C

Receptor sequence
>5nj8C (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
KSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKS
FFDVALKREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQ
QSDVIHQSVYELIHTEDRAEFQRQENSPLMERCFICRLRCLFLAMNFQGK
LKYLHGQKKDGSILPPQLALFAIATP
3D structure
PDB5nj8 Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.
ChainC
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R40 N44 D65 K66 R9 N13 D34 K35 PDBbind-CN: Kd=90nM
BS02 dna C R38 H39 R42 R7 H8 R11 PDBbind-CN: Kd=90nM
BS03 ER3 C L112 E116 L63 E67
BS04 ER3 C E165 E169 E116 E120
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006805 xenobiotic metabolic process
GO:0009410 response to xenobiotic stimulus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5nj8, PDBe:5nj8, PDBj:5nj8
PDBsum5nj8
PubMed28602820
UniProtP35869|AHR_HUMAN Aryl hydrocarbon receptor (Gene Name=AHR)

[Back to BioLiP]