Structure of PDB 5nbm Chain C

Receptor sequence
>5nbmC (length=364) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHKDSYVGDEAQS
KRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPM
NPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVT
HVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVR
DIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEA
LFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIA
ERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQ
EYDESGPSIVHHKC
3D structure
PDB5nbm The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling.
ChainC
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C G13 S14 G15 K18 G156 D157 G158 V159 K213 E214 G301 G302 M305 F306 G12 S13 G14 K17 G146 D147 G148 V149 K203 E204 G291 G292 M295 F296
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0000011 vacuole inheritance
GO:0006281 DNA repair
GO:0006338 chromatin remodeling
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0006897 endocytosis
GO:0009306 protein secretion
GO:0030010 establishment of cell polarity
GO:0030476 ascospore wall assembly
GO:1902404 mitotic actomyosin contractile ring contraction
Cellular Component
GO:0000142 cellular bud neck contractile ring
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0030479 actin cortical patch
GO:0031011 Ino80 complex
GO:0032432 actin filament bundle
GO:0035267 NuA4 histone acetyltransferase complex
GO:0043232 intracellular non-membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nbm, PDBe:5nbm, PDBj:5nbm
PDBsum5nbm
PubMed30177756
UniProtP60010|ACT_YEAST Actin (Gene Name=ACT1)

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