Structure of PDB 5mra Chain C

Receptor sequence
>5mraC (length=167) Species: 9606 (Homo sapiens) [Search protein sequence]
MDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSM
LDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTT
MGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQ
GVVNFPYDDFIQCVMSV
3D structure
PDB5mra Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells.
ChainC
Resolution3.74 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F95 G118 V120
Catalytic site (residue number reindexed from 1) F64 G87 V89
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C A43 D46 Q48 E53 A12 D15 Q17 E22
BS02 MG C D83 R84 D52 R53
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:5mra, PDBe:5mra, PDBj:5mra
PDBsum5mra
PubMed28726784
UniProtP30626|SORCN_HUMAN Sorcin (Gene Name=SRI)

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