Structure of PDB 5mei Chain C

Receptor sequence

>5meiC (length=214) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

VVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVC
LADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQT
LIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVIS
EILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLK
QPKFDVGALMALHG

3D structure

PDB

5mei Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.

Chain

Resolution

3.5 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	C	P23 K27 V65 V114 K116 W117 Q118 L120 R136 F138 Q146 N148 Q149 V150 K151 H153 Y155 Q157 S158 S159 H160 R165 K202 D203 I204 F205 P206 K216	P4 K8 V46 V95 K97 W98 Q99 L101 R117 F119 Q127 N129 Q130 V131 K132 H134 Y136 Q138 S139 S140 H141 R146 K183 D184 I185 F186 P187 K197
BS02	OHX	C	Q157 H160	Q138 H141

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5mei, PDBe:5mei, PDBj:5mei
PDBsum	5mei
PubMed	28457705
UniProt	P33442\|RS3A1_YEAST Small ribosomal subunit protein eS1A (Gene Name=RPS1A)

[Back to BioLiP]