Structure of PDB 5m5k Chain C

Receptor sequence
>5m5kC (length=471) Species: 29448 (Bradyrhizobium elkanii) [Search protein sequence]
AKPGFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGAR
IAGSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPV
FAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQG
DTAFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGV
HRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVML
SGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVT
MEDAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASL
RNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFT
NQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRK
DQADYIGVKQEGPYKSDHYRY
3D structure
PDB5m5k Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii.
ChainC
Resolution1.84 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H58 S81 S86 D135 E197 N222 K227 D231 N232 C236 H342 H392 S400 Q404
Catalytic site (residue number reindexed from 1) H56 S79 S84 D133 E195 N220 K225 D229 N230 C234 H340 H390 S398 Q402
Enzyme Commision number 3.13.2.1: adenosylhomocysteinase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004013 adenosylhomocysteinase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0033353 S-adenosylmethionine cycle
GO:0071269 L-homocysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5m5k, PDBe:5m5k, PDBj:5m5k
PDBsum5m5k
PubMed28512574
UniProtA0A087WNH6|SAHH_BRAEL Adenosylhomocysteinase (Gene Name=ahcY)

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