Structure of PDB 5m3h Chain C

Receptor sequence
>5m3hC (length=730) Species: 11320 (Influenza A virus) [Search protein sequence]
SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMK
WMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTW
WNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDIN
PGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKI
SPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGG
EAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEIL
RSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGN
LQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLM
ITLMVFSQEEKMLKAVRGDLNFVNQRLNPMYQLLRHFQKDSSTLLKNWGT
EEIDPIMGIAGIMPDGTINKTQTLMGVRLSQIRVNIDKYLRVRNEKGELL
ISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKT
QWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDS
IQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQME
NVIIVLGKSVGSPERSILTESSSIESAVLRGFLILGKANSKYGPVLTIGE
LDKLGRGEKANVLIGQGDTVLVMKRKRDSS
3D structure
PDB5m3h Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna C S36 G37 R38 E40 R46 W49 S38 G39 R40 E42 R48 W51
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5m3h, PDBe:5m3h, PDBj:5m3h
PDBsum5m3h
PubMed28002402
UniProtH6QM90

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