Structure of PDB 5lhz Chain C

Receptor sequence
>5lhzC (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
LLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTT
RYGENEKLPDYIKQKLQCLSSILLMFS
3D structure
PDB5lhz A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
ChainC
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C Q950 Q953 C954 S956 S957 S963 Q64 Q67 C68 S70 S71 S77
BS02 peptide C Q901 Q920 A921 V923 E942 K943 L944 Q953 Q15 Q34 A35 V37 E56 K57 L58 Q67
External links
PDB RCSB:5lhz, PDBe:5lhz, PDBj:5lhz
PDBsum5lhz
PubMed28202467
UniProtO00444|PLK4_HUMAN Serine/threonine-protein kinase PLK4 (Gene Name=PLK4)

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