Structure of PDB 5laa Chain C

Receptor sequence
>5laaC (length=160) Species: 523846 (Methanothermus fervidus DSM 2088) [Search protein sequence]
HMVKKKEPAEGWPVVSGDYIVGDPESPVAAVTLASHIEDIPIDAGAAIAG
PCKTENLGIEKVIANIISNPNIRFLVLCGSEVQGHIVGQSMKALHKNGVD
DKRKIIGAKGAIPYIENLPEEALERFQKQVEIVDLIDVEDADQIKEKVKE
CIEKDPGAFE
3D structure
PDB5laa MtrA of the sodium ion pumping methyltransferase binds cobalamin in a unique mode.
ChainC
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.86: Transferred entry: 7.2.1.4.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 B12 C G16 D17 Y18 A29 V30 I47 G49 P50 K52 T53 N55 G57 K60 V61 Q82 H84 A110 I111 G17 D18 Y19 A30 V31 I48 G50 P51 K53 T54 N56 G58 K61 V62 Q83 H85 A111 I112
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0030269 tetrahydromethanopterin S-methyltransferase activity
GO:0050897 cobalt ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0006814 sodium ion transport
GO:0015948 methanogenesis
GO:0019386 methanogenesis, from carbon dioxide
GO:0032259 methylation
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5laa, PDBe:5laa, PDBj:5laa
PDBsum5laa
PubMed27324530
UniProtE3GWY7

[Back to BioLiP]