Structure of PDB 5k50 Chain C

Receptor sequence
>5k50C (length=319) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
PRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKGVE
KLDCLDSNGFEKLVKEFKPTWMYHLPAIMSVRGEAEPDLAMDINVNTTRY
ALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVYTE
LLGTWYRQKYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQKKC
VCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVYNITGFSFSPSEL
RFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYDID
MMSEDMLRQIPILHGLPSL
3D structure
PDB5k50 Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
ChainC
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.103: L-threonine 3-dehydrogenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD C G1009 G1012 Q1013 I1014 D1035 V1036 D1055 C1056 L1077 P1078 A1079 M1081 T1119 Y1144 K1148 L1171 P1172 I1174 G7 G10 Q11 I12 D33 V34 D53 C54 L75 P76 A77 M79 T117 Y142 K146 L169 P170 I172
BS02 ALO C M1081 S1082 T1119 Y1144 A1185 W1280 M79 S80 T117 Y142 A183 W278
External links