Structure of PDB 5jwq Chain C

Receptor sequence
>5jwqC (length=408) Species: 197221 (Thermosynechococcus vestitus BP-1) [Search protein sequence]
VKKIPTMIEGFDDISHGGLPQGRTTLVSGTSGTGKTLFAVQFLYNGITIF
NEPGIFVTFEESPQDIIKNALSFGWNLQSLIDQGKLFILDASPDPDGQEV
AGDFDLSALIERIQYAIRKYKATRVSIDSVTAVFQQYDAASVVRREIFRL
AFRLKQLGVTTIMTTEVARFGVEEFVSDNVVILRNVLEGERRRRTVEILK
LRGTTHMKGEYPFTINNGINIFPLGANVRVSSGVKTLDEMCGFFKDSIIL
ATGATGTGKTLLVSKFLETGCQQGERESRAQLSRNASSWGIDFEELERPE
SAGLEDHLQIIKSEIADFKPSRVAIDSLSALARGVSNNAFRQFVIGVTGF
AKQEEITGFFTNTTDQFMGSNSITESHIETITDTILLLQMSRAINVFKMR
GSWHDKGI
3D structure
PDB5jwq Structural basis of the day-night transition in a bacterial circadian clock.
ChainC
Resolution3.871 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C K225 L226 R227 G228 T229 T230 K200 L201 R202 G203 T204 T205
BS02 ADP C G50 T51 G52 K53 T54 L55 N87 S90 F91 I240 G32 T33 G34 K35 T36 L37 N69 S72 F73 I215
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0044024 histone H2AS1 kinase activity
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0007623 circadian rhythm
GO:0016310 phosphorylation
GO:0042752 regulation of circadian rhythm
GO:0046777 protein autophosphorylation
GO:0048511 rhythmic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5jwq, PDBe:5jwq, PDBj:5jwq
PDBsum5jwq
PubMed28302851
UniProtQ79V60|KAIC_THEVB Circadian clock oscillator protein KaiC (Gene Name=kaiC)

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