Structure of PDB 5jjm Chain C

Receptor sequence
>5jjmC (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
ECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVK
WAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPD
LVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIP
VDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQ
PIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFH
3D structure
PDB5jjm Structure of the homodimeric androgen receptor ligand-binding domain.
ChainC
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E668 D839 P849 C852 E1 D172 P182 C185
BS02 peptide C K720 M734 M894 K53 M67 M227
BS03 DHT C L701 L704 N705 L707 Q711 M745 M749 F764 T877 L34 L37 N38 L40 Q44 M78 M82 F97 T210 BindingDB: IC50=>10000nM,EC50=6nM,Ki=0.2nM
External links
PDB RCSB:5jjm, PDBe:5jjm, PDBj:5jjm
PDBsum5jjm
PubMed28165461
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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