Structure of PDB 5izu Chain C

Receptor sequence
>5izuC (length=124) Species: 10090 (Mus musculus) [Search protein sequence]
RTKRLFRHYTVGSYDSLTSHSDYVIDDKVAILQKRDHEGFGFVLRGAKAE
TPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVG
HKQVVGLIRQGGNRLVMKVVSVTR
3D structure
PDB5izu A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function
ChainC
Resolution2.494 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C T543 K544 R545 L546 F547 R548 H549 Y550 T551 L558 T2 K3 R4 L5 F6 R7 H8 Y9 T10 L17
BS02 peptide C G580 F581 G582 F583 V584 L585 R586 G587 A588 K589 Y608 E610 D613 H642 V646 G39 F40 G41 F42 V43 L44 R45 G46 A47 K48 Y67 E69 D72 H101 V105
External links
PDB RCSB:5izu, PDBe:5izu, PDBj:5izu
PDBsum5izu
PubMed27185935
UniProtQ4ACU6|SHAN3_MOUSE SH3 and multiple ankyrin repeat domains protein 3 (Gene Name=Shank3)

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