Structure of PDB 5izd Chain C

Receptor sequence
>5izdC (length=484) Species: 2303 (Thermoplasma acidophilum) [Search protein sequence]
MDTKLYIDGQWVNSSSGKTVDKYSPVTGQVIGRFEAATRDDVDRAIDAAE
DAFWAWNDLGSVERSKIIYRAKELIEKNRAELENIIMEENGKPVKEAKEE
VDGVIDQIQYYAEWARKLNGEVVEGTSSHRKIFQYKVPYGIVVALTPWNF
PAGMVARKLAPALLTGNTVVLKPSSDTPGSAEWIVRKFVEAGVPKGVLNF
ITGRGSEIGDYIVEHKKVNLITMTGSTATGQRIMQKASANMAKLILELGG
KAPFMVWKDADMDNALKTLLWAKYWNAGQSCIAAERLYVHEDIYDTFMSR
FVELSRKLALGDPKNADMGPLINKGALQATSEIVEEAKESGAKILFGGSQ
PRNGYFFLPTIIGDQKSKIFQEEIFAPVIGARKISSVEEMYDLANDSKYG
LASYLFTKDPNIIFEASERIRFGELYVNMPGPEASQGYHTGFRMTGQAGE
GSKYGISEYLKLKNIYVDYSGKPLHINTVRDDLF
3D structure
PDB5izd Structure of wild-type glyceraldehyde dehydrogenase from Thermoplasma acidophilum in complex with NADP
ChainC
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N149 K172 E247 C281 E381 E458
Catalytic site (residue number reindexed from 1) N149 K172 E247 C281 E373 E450
Enzyme Commision number 1.2.1.89: D-glyceraldehyde dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP C L145 T146 W148 K172 S174 S175 R204 G205 G209 S226 T229 L145 T146 W148 K172 S174 S175 R204 G205 G209 S226 T229
Gene Ontology
Molecular Function
GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0042803 protein homodimerization activity
GO:0043796 glyceraldehyde dehydrogenase (NADP+) activity
Biological Process
GO:0006096 glycolytic process
GO:0009255 Entner-Doudoroff pathway through 6-phosphogluconate
GO:0009450 gamma-aminobutyric acid catabolic process
GO:0051289 protein homotetramerization
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:5izd, PDBe:5izd, PDBj:5izd
PDBsum5izd
PubMed
UniProtQ9HK01|GADH_THEAC D-glyceraldehyde dehydrogenase (NADP(+)) (Gene Name=Ta0809)

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