Structure of PDB 5iy6 Chain C

Receptor sequence
>5iy6C (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWV
QIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVE
FTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILI
VKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKP
EEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALS
GLKKKLSDLQTQLSHEIQSDVLTIN
3D structure
PDB5iy6 Near-atomic resolution visualization of human transcription promoter opening.
ChainC
Resolution7.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C C88 C90 C94 C97 C88 C90 C94 C97
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5iy6, PDBe:5iy6, PDBj:5iy6
PDBsum5iy6
PubMed27193682
UniProtP19387|RPB3_HUMAN DNA-directed RNA polymerase II subunit RPB3 (Gene Name=POLR2C)

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