Structure of PDB 5irm Chain C

Receptor sequence
>5irmC (length=770) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
EFEAAACKKYMSKLRTIVAAQSRFLENLCLEDIYTENTLEVRTEVGSPAA
LGLEELFSPNGHLNEDADTVLVVGEAGSGKSTLLQQVHLLWATGQDFQEF
LFVFPFSCRQLQCVARPLSVMTLLFEHCCWPDVGQQDVFQFLLDHPDRIL
LTFDGFDEFKFKFTDHERHCSPTDPTSVQTLLFNLLQGNLLKNARKVLTS
RPDAVSAFLRKYVRTEFNLKGFSEEGIELYLRKCHREPGVADRLIHLLQT
TSALHGLCHLPVFSWMVSKCHQELLLQDGGSPKTTTDMYLLILQHFLRHA
GPSLLQGRLPTLLRLGQLALWGLGMCCYVFSAQQLQAAQVDPDDISLGFL
VQAQGVVPGSTAPLEFLHITFQCFLAAFYLVLSTDVPTASLRYLFNCEST
VAALLQKTEPHNLQITAAFLAGLLSREHRDLLAACQASERSLLRRRACAR
WCLARSLHKHFRSIAMPGFLWLIRSLYEMQEERLAQEAVRGLNVEHLKLT
FCGVGPAECAALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLGACKAL
YLRDNNISDRGICKLIEHALHCEQLQKLALFNNKLTDGCAHSVAQLLACK
QNFLALRLGNNHITAEGAQVLAEGLRDNSSLQFLGFWGNKVGDKGAQALA
EALSDHQSLKWLSLVGNNIGSVGAQALASMLEKNVALEELCLEENHLQDA
GVCSLAEGLKRNSSLKVLKLSNNCITFVGAEALLQALASNDTILEVWLRG
NPFSPEEMEALSHRDSRLLL
3D structure
PDB5irm Crystal structure of NOD2 and its implications in human disease.
ChainC
Resolution3.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C Y232 T233 G282 G284 K285 S286 T287 F427 Y435 P466 Y34 T35 G77 G79 K80 S81 T82 F222 Y230 P261
External links
PDB RCSB:5irm, PDBe:5irm, PDBj:5irm
PDBsum5irm
PubMed27283905
UniProtG1T469|NOD2_RABIT Nucleotide-binding oligomerization domain-containing protein 2 (Gene Name=NOD2)

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