Structure of PDB 5gue Chain C

Receptor sequence
>5gueC (length=285) Species: 67327 (Streptomyces melanosporofaciens) [Search protein sequence]
DIGRSSVRPYLEECTRRFQEMFDRHVVTRPTKVELTDAELREVIDDCNAA
VAPLGKTVSDERWISYVGVVLWSQSPRHIKDMEAFKAVCVLNCVTFVWDD
MDPALHDFGLFLPQLRKICEKYYGPEDAEVAYEAARAFVTSDHMFRDSPI
KAALCTTSPEQYFRFRVTDIGVDFWMKMSYPIYRHPEFTEHAKTSLAARM
TTRGLTIVNDFYSYDREVSLGQITNCFRLCDVSDETAFKEFFQARLDDMI
EDIECIKAFDQLTQDVFLDLIYGNFVWTTSNKRYK
3D structure
PDB5gue Structural Insights into the CotB2-Catalyzed Cyclization of Geranylgeranyl Diphosphate to the Diterpene Cyclooctat-9-en-7-ol
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.146: cyclooctat-9-en-7-ol synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GGS C N103 F107 D110 G182 W186 L216 N220 S224 R227 E228 R294 Y295 N92 F96 D99 G171 W175 L205 N209 S213 R216 E217 R283 Y284
BS02 MG C N220 S224 E228 N209 S213 E217
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5gue, PDBe:5gue, PDBj:5gue
PDBsum5gue
PubMed28463490
UniProtC9K1X5|COTB2_STRMJ Cyclooctat-9-en-7-ol synthase (Gene Name=CotB2)

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