Structure of PDB 5gsu Chain C

Receptor sequence
>5gsuC (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
KSKSRSSRAGLQFPVGRIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEI
LELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQ
AVLLPK
3D structure
PDB5gsu Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
ChainC
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C K15 K17 R19 R34 R44 R79 K1 K3 R5 R20 R30 R65
BS02 dna C R31 R44 G46 A47 K77 T78 R79 R17 R30 G32 A33 K63 T64 R65
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0031507 heterochromatin formation
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0000786 nucleosome
GO:0001674 female germ cell nucleus
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:5gsu, PDBe:5gsu, PDBj:5gsu
PDBsum5gsu
PubMed27992841
UniProtQ96QV6|H2A1A_HUMAN Histone H2A type 1-A (Gene Name=H2AC1)

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