Structure of PDB 5g5h Chain C

Receptor sequence
>5g5hC (length=730) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEEAPNAAY
GYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGVLGKGDKNTARLL
GGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAV
NQPPEDTPDKNVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWD
GNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGGGFGGKLFLRS
DALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKIT
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMR
APGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPAGPTRCFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFHNNLLEKSGAR
VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSF
PVSAGSGGQWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITN
GTRSATLHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
EVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGY
FVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSA
AIANAVYNATGIRVRDYPITLDKLLDKLPD
3D structure
PDB5g5h The Escherichia Coli Periplasmic Aldehyde Oxidoreductase is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes.
ChainC
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) Q211 L246 P316 Q322 R350 E692 L693
Catalytic site (residue number reindexed from 1) Q211 L246 P316 Q322 R350 E692 L693
Enzyme Commision number 1.2.99.6: carboxylate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MCN C G241 F242 R350 I468 G469 T470 G471 G507 Q509 G511 A512 L617 N618 T621 Q625 K688 G689 V690 G691 E692 G241 F242 R350 I468 G469 T470 G471 G507 Q509 G511 A512 L617 N618 T621 Q625 K688 G689 V690 G691 E692
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors
GO:0030151 molybdenum ion binding
GO:0046872 metal ion binding
GO:0047770 carboxylate reductase activity
Biological Process
GO:0006974 DNA damage response
GO:0009056 catabolic process
GO:0110095 cellular detoxification of aldehyde
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:1990204 oxidoreductase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5g5h, PDBe:5g5h, PDBj:5g5h
PDBsum5g5h
PubMed27622978
UniProtP77489|PAOC_ECOLI Aldehyde oxidoreductase molybdenum-binding subunit PaoC (Gene Name=paoC)

[Back to BioLiP]