Structure of PDB 5fii Chain C

Receptor sequence
>5fiiC (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
AISLIFSLKEEVGALAKVLRLFEENDVNLTHIESRPSKKDEYEFFTHLDK
RSLPALTNIIKILRHDIGATVHELSR
3D structure
PDB5fii Structural Basis for Ligand-Dependent Dimerization of Phenylalanine Hydroxylase Regulatory Domain.
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.16.1: phenylalanine 4-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PHE C E43 E44 L48 S67 Y77 F79 E10 E11 L15 S34 Y42 F44
BS02 PHE C N61 L62 H64 N28 L29 H31
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
Biological Process
GO:0009072 aromatic amino acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5fii, PDBe:5fii, PDBj:5fii
PDBsum5fii
PubMed27049649
UniProtP00439|PH4H_HUMAN Phenylalanine-4-hydroxylase (Gene Name=PAH)

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