Structure of PDB 5fh8 Chain C

Receptor sequence
>5fh8C (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
YMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKP
MDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLH
KVLLETRRD
3D structure
PDB5fh8 Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex.
ChainC
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5XK C I683 F684 L687 Y696 M731 A735 N739 I745 I30 F31 L34 Y43 M78 A82 N86 I92 MOAD: Kd=170nM
Gene Ontology
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0016586 RSC-type complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5fh8, PDBe:5fh8, PDBj:5fh8
PDBsum5fh8
PubMed27119626
UniProtQ86U86|PB1_HUMAN Protein polybromo-1 (Gene Name=PBRM1)

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