Structure of PDB 5f1c Chain C

Receptor sequence
>5f1cC (length=344) Species: 34609 (Amblyomma maculatum) [Search protein sequence]
VLNRLIQLLILGYIIGYVIIYQKGYQQFSTFNAATTTKVKGVVSTKNLSD
DAFYPFLSDKTVYKRVWDIADIVVPPEESNQFFVTTNLIITPSQEIKTCP
EDPSIKEAHCKSENDTTSCTAGKSIMIGNGVMTGRCVQAAKPQETLHVCE
ISGWCPVEQDYGPLKDGTPLLSDVQNFTVLIKNYIEFSLFHVRRSNLHDI
ENSTYLKYCRYHPEKDPHCPVFRIGDMVDAAGEDFDDVAAKGGVIQVLIS
WDCNLDYDVKYCIPNYSFLRLDDPKTVLAKGWNFRYPKYYNEKERSLVKA
YGITFVILVQGRAGKLSPIPIAINIGSGLGLMVVATVLCDLVVL
3D structure
PDB5f1c Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C K66 V67 K68 T206 V207 L208 K38 V39 K40 T178 V179 L180
BS02 ATP C D188 N311 R313 K327 D160 N283 R285 K299
BS03 ZN C E141 H175 E113 H147
Gene Ontology
Molecular Function
GO:0001614 purinergic nucleotide receptor activity
GO:0004931 extracellularly ATP-gated monoatomic cation channel activity
GO:0005524 ATP binding
GO:0015267 channel activity
GO:0046872 metal ion binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0007165 signal transduction
GO:0033198 response to ATP
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0060079 excitatory postsynaptic potential
GO:0070588 calcium ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0098794 postsynapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5f1c, PDBe:5f1c, PDBj:5f1c
PDBsum5f1c
PubMed26804916
UniProtG3MM57

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