Structure of PDB 5ewm Chain C

Receptor sequence
>5ewmC (length=356) Species: 8355 (Xenopus laevis) [Search protein sequence]
DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLQATSVTHRPNAI
QMALSVCEDLISSQVYAILVSHPLTPTPISYTAGFYRIPVIGLTTRMSIY
SDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQK
KLETLLEGPKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATA
VYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAH
ISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKY
PDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFNGSYIIQNDRKII
WPGGET
3D structure
PDB5ewm A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
ChainC
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5SM C Y109 I133 Y81 I105
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5ewm, PDBe:5ewm, PDBj:5ewm
PDBsum5ewm
PubMed26912815
UniProtA0A1L8F5J9|NMDZ1_XENLA Glutamate receptor ionotropic, NMDA 1 (Gene Name=grin1)

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