Structure of PDB 5ent Chain C

Receptor sequence
>5entC (length=581) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
APPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTV
QITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLM
VVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWM
NPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQT
RLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASG
LGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYQGVFMTMVQLP
AGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFV
SLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAITATGFDFE
LIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQ
EKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLP
DDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAP
GKSTGEAMELMEQLASKLPTGVGYDWTGMSY
3D structure
PDB5ent Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MIY C F178 G179 N274 I277 F140 G141 N236 I239
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ent, PDBe:5ent, PDBj:5ent
PDBsum5ent
PubMed26976576
UniProtP31224|ACRB_ECOLI Multidrug efflux pump subunit AcrB (Gene Name=acrB)

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