Structure of PDB 5ej2 Chain C

Receptor sequence
>5ej2C (length=277) Species: 243243 (Mycobacterium avium 104) [Search protein sequence]
TGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHS
TPEDLAETADLVKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIV
ANAGVGTDGRKLHKIRDNVWQDMIDINLTGVWHTVKAGVPHVLSGGRGGS
IVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVELGPHMIRVNAVLPT
QVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWVDASDISN
AVLFLASDESRYVTGVSLPVDAGSLLK
3D structure
PDB5ej2 Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
ChainC
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G26 S165 Y178 K182
Catalytic site (residue number reindexed from 1) G17 S156 Y169 K173
Enzyme Commision number 1.1.1.275: (+)-trans-carveol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C G22 R25 G26 Q27 D46 I47 I51 S59 D84 V85 N111 A112 G113 V114 T163 S165 Y178 K182 Q210 V211 T213 M215 V216 G13 R16 G17 Q18 D37 I38 I42 S50 D75 V76 N102 A103 G104 V105 T154 S156 Y169 K173 Q201 V202 T204 M206 V207
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0033702 (+)-trans-carveol dehydrogenase activity

View graph for
Molecular Function
External links
PDB RCSB:5ej2, PDBe:5ej2, PDBj:5ej2
PDBsum5ej2
PubMed28120876
UniProtA0A0H2ZYS9

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