Structure of PDB 5eel Chain C

Receptor sequence
>5eelC (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
RTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQK
VKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHC
CTRVAL
3D structure
PDB5eel Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
ChainC
Resolution2.47 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C H433 E440 L444 R529 V530 H7 E14 L18 R103 V104
BS02 peptide C R438 R462 K478 H479 Y480 L481 L483 M495 R12 R36 K52 H53 Y54 L55 L57 M69
External links
PDB RCSB:5eel, PDBe:5eel, PDBj:5eel
PDBsum5eel
PubMed27257138
UniProtQ14451|GRB7_HUMAN Growth factor receptor-bound protein 7 (Gene Name=GRB7)

[Back to BioLiP]