Structure of PDB 5e5c Chain C

Receptor sequence
>5e5cC (length=479) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MSLLIRGATVVTHEESYRADVLCANGLIQAIGENLETPSGCDVLDGGGQY
LMPGGIDPHTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQ
SLLEAFHTWRGWAQKSAADYGFHVAITWWSDEVAREMGELVAQHGVNSFK
HFMAYKNAIMAADDTLVASFERCLELGAVPTVHAENGELVFHLQQKLLAQ
GLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYLVHISSREALDEIA
YARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVEHQEA
LWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLW
DAGVNSGRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQG
SRTLSAATHHQRVDFNIFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAG
RYVERPAYPSVYEVLGRRAERQRPVAVER
3D structure
PDB5e5c Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1: Insights into the molecular basis of formation of a dimer
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.2: dihydropyrimidinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C K150 H183 H239 K150 H183 H239
BS02 ZN C H59 H61 K150 D316 H59 H61 K150 D316
Gene Ontology
Molecular Function
GO:0004157 dihydropyrimidinase activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:5e5c, PDBe:5e5c, PDBj:5e5c
PDBsum5e5c
PubMed27576201
UniProtQ9I676|HYDA_PSEAE D-hydantoinase/dihydropyrimidinase (Gene Name=dht)

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