Structure of PDB 5dv7 Chain C

Receptor sequence
>5dv7C (length=137) Species: 10090 (Mus musculus) [Search protein sequence]
MNALMRLNQLKPGLQYKLISQTGPVHAPIFTMSVEVDGSNFEASGPSKKT
AKLHVAVKVLQDMGLPILTKHGKNPVMELNEKRRGLKYELISETGGSHDK
RFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFP
3D structure
PDB5dv7 Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA.
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C Q411 S550 F555 K573 Q9 S97 F102 K120 PDBbind-CN: Kd=2.4uM
BS02 rna C N404 L406 M407 N527 V529 M530 N533 G549 S550 N2 L4 M5 N74 V76 M77 N80 G96 S97 PDBbind-CN: Kd=2.4uM
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5dv7, PDBe:5dv7, PDBj:5dv7
PDBsum5dv7
PubMed26712564
UniProtQ9Z1X4|ILF3_MOUSE Interleukin enhancer-binding factor 3 (Gene Name=Ilf3)

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