Structure of PDB 5dnm Chain C

Receptor sequence
>5dnmC (length=106) Species: 8355 (Xenopus laevis) [Search protein sequence]
AKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEIL
ELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQS
VLLPKK
3D structure
PDB5dnm Allosteric cross-talk in chromatin can mediate drug-drug synergy
ChainC
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C A14 K15 T16 R17 R20 R29 R32 R42 R77 A1 K2 T3 R4 R7 R16 R19 R29 R64
BS02 dna C R29 R35 R42 A45 K75 T76 R77 R16 R22 R29 A32 K62 T63 R64
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5dnm, PDBe:5dnm, PDBj:5dnm
PDBsum5dnm
PubMed28358030
UniProtP06897|H2A1_XENLA Histone H2A type 1

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