Structure of PDB 5cd4 Chain C

Receptor sequence
>5cd4C (length=356) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRK
SGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSV
DEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAI
RVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWF
TAVDDLQESAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIAT
HVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKD
GFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDVKQMPTLEQLKSWV
RNNGEA
3D structure
PDB5cd4 Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.
ChainC
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna C N19 R20 D21 D22 K27 Q42 S43 K45 R46 M166 F200 T201 V203 L214 A265 K266 N19 R20 D21 D22 K27 Q42 S43 K45 R46 M166 F200 T201 V203 L212 A263 K264
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5cd4, PDBe:5cd4, PDBj:5cd4
PDBsum5cd4
PubMed26243775
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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