Structure of PDB 5c8w Chain C

Receptor sequence
>5c8wC (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
VRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQ
GEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAILYNCTRTASVKA
ITNVKTWALDREVFQNIMRRT
3D structure
PDB5c8w Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
ChainC
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG C V215 F231 G232 L234 A235 R242 T243 V67 F83 G84 L86 A87 R94 T95 MOAD: Kd=43.8nM
External links
PDB RCSB:5c8w, PDBe:5c8w, PDBj:5c8w
PDBsum5c8w
PubMed26769964
UniProtQ13237|KGP2_HUMAN cGMP-dependent protein kinase 2 (Gene Name=PRKG2)

[Back to BioLiP]