Structure of PDB 5c3p Chain C

Receptor sequence
>5c3pC (length=325) Species: 5141 (Neurospora crassa) [Search protein sequence]
MEKAAVNEDGLVIPLIDFSKFLEGDETLKLETAKAILHGFQTAGFIYLKN
IPIQPDFREHVFNTSAKFFKLPKEKKLEVGNRGYSAPGREKVTQLTDPAE
IEKIRSAAPDIKESYEIGREDEPGHPNPWPAEQDDLVGFKSTMNNFFDQC
KALHIEVMRAIAVGMGIDANYFDSFVDVGDNILRLLHYPAVKSEVFKINP
GQVRAGEHTDYGSITLLFQDSRGGLQVKSPNGQFIDATPIENTVVVNAGD
LLARWSNDTIKSTVHRVVEPPKQEDVHPPRYSIAYFCNPNHKSYIEAIPG
TYAAESERKYEGINSGKYLVQRLAA
3D structure
PDB5c3p Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
ChainC
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R190 A211 H214 D216 H271
Catalytic site (residue number reindexed from 1) R184 A205 H208 D210 H265
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AKG C R190 Y194 H214 L223 H271 V273 R286 S288 F292 R184 Y188 H208 L217 H265 V267 R280 S282 F286 MOAD: Kd=34.4uM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0044283 small molecule biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5c3p, PDBe:5c3p, PDBj:5c3p
PDBsum5c3p
PubMed26429971
UniProtQ7RYZ9

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