Structure of PDB 5brm Chain C

Receptor sequence
>5brmC (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTI
LKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRREL
APLQELIEKL
3D structure
PDB5brm Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
ChainC
Resolution2.651 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E94 Y95 H96 R154 R157 Y163 H164 F167 E176 N180 E200 L207 E43 Y44 H45 R103 R106 Y112 H113 F116 E125 N129 E149 L156
BS02 peptide C F65 N66 N69 P133 S134 K135 I136 F14 N15 N18 P82 S83 K84 I85
BS03 ZN C C79 C84 H161 H166 C28 C33 H110 H115
External links
PDB RCSB:5brm, PDBe:5brm, PDBj:5brm
PDBsum5brm
PubMed26108669
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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