Structure of PDB 5bq2 Chain C

Receptor sequence
>5bq2C (length=425) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HHHHMDKLIITGGNRLDGEIRISGAKNSALPILAATLLADTPVTVCNLPH
LHDITTMIELFGRMGVQPIIDEKLNVEVDASSIKTLVAPYELVKTMRASI
LVLGPMLARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAQIEVEGGYIK
AKAPAGGLRGGHFFFDTVSVTGTENLMMAAALANGRTVLQNAAREPEVVD
LANCLNAMGANVQGAGSDTIVIEGVKRLGGARYDVLPDRIETGTYLVAAA
ATGGRVKLKDTDPTILEAVLQKLEEAGAHISTGSNWIELDMKGNRPKAVN
VRTAPYPAFPTDMQAQFISMNAVAEGTGAVIETVFENRFMHVYEMNRMGA
QILVEGNTAIVTGVPKLKGAPVMATDLRASASLVIAGLVAEGDTLIDRIY
HIDRGYECIEEKLQLLGAKIRRVPG
3D structure
PDB5bq2 Crystal structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (UDP-N-acetylglucosamine enolpyruvyl transferase, EPT) from Pseudomonas aeruginosa
ChainC
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K22 N23 C117 R122 D308 R400
Catalytic site (residue number reindexed from 1) K26 N27 C121 R126 D312 R404
Enzyme Commision number 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EPU C K22 N23 S121 R122 P123 V124 D125 L126 S165 V166 T167 D308 F331 L373 K26 N27 S125 R126 P127 V128 D129 L130 S169 V170 T171 D312 F335 L377
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:5bq2, PDBe:5bq2, PDBj:5bq2
PDBsum5bq2
PubMed
UniProtQ9HVW7|MURA_PSEAE UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Gene Name=murA)

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