Structure of PDB 5ajk Chain C

Receptor sequence
>5ajkC (length=139) Species: 10255 (Variola virus) [Search protein sequence]
STNILDYLSTERDHVMMAVQYYMSKQRLDDLYRQLPTKTRSYIDIINMYC
DKVNNDYNRDMNIMYDMASTESFTVYDINNEVNTILMDNKGLGVRLATIS
FITELGKRCMNPVETIKMFTLLSHTICDDCFIDYITDIS
3D structure
PDB5ajk Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
ChainC
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C D118 Y119 M126 M129 T132 E133 I140 E143 I147 G155 V156 F163 D56 Y57 M64 M67 T70 E71 I78 E81 I85 G93 V94 F101
Gene Ontology
Biological Process
GO:0033668 symbiont-mediated suppression of host apoptosis
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5ajk, PDBe:5ajk, PDBj:5ajk
PDBsum5ajk
PubMed25766319
UniProtQ85365|PG045_VARV Apoptosis regulator OPG045 (Gene Name=OPG045)

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