Structure of PDB 5a6b Chain C

Receptor sequence
>5a6bC (length=610) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
SMVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQ
LTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLN
VASAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEI
EAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVY
DLIDGMFATLSKLKTRKVNIGMDEAHLVGLGRYLILNGVVDRSLLMCQHL
ERVLDIADKYGFHCQMWSDMFEETRVYLDRLKDRVTLVYWDYYQDSEEKY
NRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRLVAIEANKACRANQIK
EVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDLDGLSAHFKTNTGLTV
EDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILCPILDQHMTPEQDKPH
FAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRIRQAYQADD
KESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHT
IATASTIYTT
3D structure
PDB5a6b A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
ChainC
Resolution1.77 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OAN C R94 D222 E223 W266 W306 Y308 Y309 W339 W373 D375 R95 D223 E224 W267 W290 Y292 Y293 W323 W357 D359 MOAD: Ki=7.9nM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0015929 hexosaminidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5a6b, PDBe:5a6b, PDBj:5a6b
PDBsum5a6b
PubMed26491009
UniProtA0A0H2US73

[Back to BioLiP]