Structure of PDB 4zxf Chain C

Receptor sequence
>4zxfC (length=307) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MAPYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFG
EYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLE
HFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGP
LIILHPHTMYNKPTQIIAPLLAKFSPRVRIDTGLDLKGITSDKAYRAFLG
SDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQD
DTINDPKGSEKFIRDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMK
QWLDKHT
3D structure
PDB4zxf Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.23: acylglycerol lipase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4S7 C G48 F49 S123 M124 L154 M159 Q165 I166 L184 L208 F218 H281 G48 F49 S123 M124 L154 M159 Q165 I166 L184 L208 F218 H281
Gene Ontology
Molecular Function
GO:0016298 lipase activity
GO:0016787 hydrolase activity
GO:0017171 serine hydrolase activity
GO:0047372 monoacylglycerol lipase activity
Biological Process
GO:0006639 acylglycerol metabolic process
GO:0006641 triglyceride metabolic process
GO:0019433 triglyceride catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005811 lipid droplet
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zxf, PDBe:4zxf, PDBj:4zxf
PDBsum4zxf
PubMed26869448
UniProtP28321|MGLL_YEAST Monoglyceride lipase (Gene Name=YJU3)

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