Structure of PDB 4zq9 Chain C

Receptor sequence
>4zq9C (length=187) Species: 648242 (Adeno-associated virus 2 Srivastava/1982) [Search protein sequence]
PGFYEIVIKVPSDSDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKL
QRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFL
SQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLLP
KTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHV
3D structure
PDB4zq9 Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K101 M103 V104 R107 F108 Q111 R138 K92 M94 V95 R98 F99 Q102 R129 PDBbind-CN: Kd=128nM
BS02 dna C S102 M103 G106 K136 R138 G142 G143 G144 N145 S93 M94 G97 K127 R129 G133 G134 G135 N136 PDBbind-CN: Kd=128nM
External links
PDB RCSB:4zq9, PDBe:4zq9, PDBj:4zq9
PDBsum4zq9
PubMed26370092
UniProtP03132|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)

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